Clambake Beta Program
Clambake: Expanding Capabilities with Oxymax-CLAMS
Accurately determining subject energy expenditure is a cornerstone of metabolic research, offering crucial insights into metabolic rates and facilitating the diagnosis and management of conditions like obesity and diabetes. This precision is vital for developing targeted nutritional and exercise interventions. Beyond individual applications, precise energy expenditure measurement also informs public health strategies, enhances our understanding of fundamental energy metabolism processes, and supports personalized medicine by addressing the diverse metabolic responses among individuals.
Key Features
Clambake offers a sophisticated approach to estimating energy expenditure by integrating measurements of basal metabolic rate (BMR), the thermic effect of food (TEF), activity-induced energy expenditure, and adaptive thermogenesis.
- Adaptive Thermogenesis: Adjusts energy expenditure in response to changes in environment, diet, or activity to maintain metabolic balance.
- Thermic Effect of Food (TEF): Energy used to digest, absorb, and metabolize nutrients after eating, influencing postprandial metabolic responses.
- Activity-Induced Energy Expenditure: Caloric expenditure from physical activity, including exercise and daily movements, crucial for managing body weight.
- Basal Metabolic Rate (BMR): Energy required for essential physiological functions at rest, serving as a baseline for total daily energy expenditure.
Developed by the Brestoff Lab at the Washington University in St. Louis, this advanced algorithm excels in accommodating previously unobserved physiological variables, ensuring that its estimates remain consistent with established biological principles. Moreover, Clambake is adept at identifying subtle metabolic variations and hidden phenotypes that may not be apparent through conventional methods.
Integration with Oxymax-CLAMS
Oxymax-CLAMS supplies the raw data for Clambake. By allowing for simulation of various environmental conditions through controlled temperature and light cycles, it provides researchers with the ability to influence a subject’s energy expenditure. The data includes parameters such as VO2, VCO2, activity counts, food intake, lean mass, and fat mass, which are integral to calculating and analyzing the subject’s energy expenditure profile in Clambake.
Benefits of Clambake
Clambake represents a transformative tool in metabolic research, offering the ability to uncover hidden phenotypes. This advanced capability not only facilitates the development of personalized treatment plans and dietary recommendations but also enhances the overall effectiveness of interventions for metabolic disorders. By integrating Clambake into your research, you gain a crucial advantage in advancing both individual and population-level understanding of metabolic health.
